Wednesday, December 7, 2005

Australian researchers say they have scientifically proven that stress causes sickness. The Garvan Institute in Sydney has discovered that a hormone, known as neuropeptide Y, (NPY) is released into the body during times of stress. Their findings show the hormone can stop the immune system from functioning properly.

“Neuropeptide Y is one of those hormones that gets unregulated or released from neurones when stressful situations occur…it’s known for example that it regulates blood pressure and heart rates so your heart rate goes up but it hasn’t been known that it actually can affect immune cells as well,” said Professor Herbert Herzog, one of the researchers.

Herzog feels it is good to finally have proof of something people have suspected for so long.

“Now we have proven without doubt that there is a direct link and that stress can weaken the immune system and that makes you more vulnerable when you for example have a cold or flu and even in the more serious situations such as cancer can be enhanced in these situations,” said Herzog.

The Garvan Institute study centres on two key events that enable the human body to recognise foreign substances and control invaders. When our body encounters a pathogen (bacteria and viruses), the immune cells retain and interrogate suspects. Their activation is made possible by NPY. These cells then return to the lymph nodes, which are found all over the body, with information about the foreign invaders. The lymph nodes are where decisions about defence are made.

“Most of us expect to come down with a cold or other illness when we are under pressure, but until now we have mostly had circumstantial evidence for a link between the brain and the immune system,” said lead Garvan researcher, associate Professor Fabienne Mackay. “During periods of stress, nerves release a lot of NPY and it gets into the bloodstream, where it directly impacts on the cells in the immune system that look out for and destroy pathogens (bacteria and viruses) in the body.”

In the case of bacteria and viruses, TH1 cells are part of the attack team that is sent out on the ‘search and destroy’ mission. But when their job is done they need to be turned ‘off’ and the immune system reset. The same hormone, NPY, that activates the sentry cells now prompts the TH1 cells to slow down and die.

“Under normal conditions, circulating immune cells produce small amounts of NPY, which enables the immune cells on sentry duty and the TH1 immune cells to operate – it’s a yin and yang kind of situation. But too much NPY means that the TH1 attack is prevented despite the foreign invaders being identified – and this is what happens during stress,” added McKay.

The impact of stress on the body has been observed in athletes. Ph. D researcher at the University of Queensland, Luke Spence, together with the Australian Institute of Sport, studied elite and recreational athletes over five months.

They found elite athletes were more susceptible to respiratory diseases under stress.

“A lot of elite athletes put themselves through vast amounts of physical stress in their training, but also their emotional, psychological stress of feeling the pressure of Australia on their shoulders, wanting to compete and wanting to do their best,” said Spence.

It’s not just athletes who are prone to stress. Pressures at work and at home may cause emotional and mental stress that can be equally damaging. Almost a third of all work absenteeism in Australia is due to illness, costing employers over $10 billion a year.

“I think it has a huge impact for the work force and also for employers – if their employees are constantly stressed, constantly under pressure, they are more likely to get sick,” Spence said.

Further research could lead to the development of new drugs which may inhibit the action of the neuropeptide Y hormone.

Herzog warns people to minimise stress before it becomes a problem.

“Relaxation methods like yoga will help you to prevent that but there will still be people out there that are not responding to that and treatment by interfering with the system will be important,” he said. “There’s obviously some time until such a treatment will be available but this is something we will definitely work towards.”

The Garvan research will be published in the Journal of Experimental Medicine, Volume 202, No. 11.

Sunday, February 8, 2009

The Japanese car making company Toyota has announced that their predicted profit loss for 2008 has tripled from their previous estimate. The company reports the loss after demand for its vehicles dropped. In December 2008, Toyota estimated its full year operating loss to be 150 billion yen (US$1.65 billion). Now the company has tripled that number, forecasting a 450 billion yen (US$4.95 billion) loss. This would be the first yearly loss at Toyota in 70 years.

The firm also said that it predicts its global sales to fall by 17.87% to 7.32 million vehicles sold, compared to last year’s 8.91 million vehicles sold. Overall for 2008, Toyota’s car sales in the United States were down 15.4%, but that number was down from 2007 in which sales dropped 18%. For the month of January alone, Toyota’s sales fell 31.7% compared to the overall U.S. sales loss of 37.1%.

As a result of the loss, 17 of the company’s 75 production lines worldwide, will be reduced to only a single shift of workers. The company also announced a full closure of all their Japanese plants for a total of 14 days between January and March 2009.

Toyota’s boss Katsuaki Watanabe described the loss as happening only “once in a hundred years”.

In January, the Japanese Nikkei newspaper said that Toyota was thinking of firing 1,000 Northern American and British workers, all of whom hold full-time positions in the company. The paper quoted Toyota’s Executive Vice President Mitsuo Kinoshita as saying that “outside of Japan, we intend to make every possible effort to protect the jobs of our employees.”

Thursday, July 3, 2014

Ian Narev, the CEO of the Commonwealth Bank of Australia, this morning “unreservedly” apologised to clients who lost money in a scandal involving the bank’s financial planning services arm.

Last week, a Senate enquiry found financial advisers from the Commonwealth Bank had made high-risk investments of clients’ money without the clients’ permission, resulting in hundreds of millions of dollars lost. The Senate enquiry called for a Royal Commission into the bank, and the Australian Securities and Investments Commission (ASIC).

Mr Narev stated the bank’s performance in providing financial advice was “unacceptable”, and the bank was launching a scheme to compensate clients who lost money due to the planners’ actions.

In a statement Mr Narev said, “Poor advice provided by some of our advisers between 2003 and 2012 caused financial loss and distress and I am truly sorry for that. […] There have been changes in management, structure and culture. We have also invested in new systems, implemented new processes, enhanced adviser supervision and improved training.”

An investigation by Fairfax Media instigated the Senate inquiry into the Commonwealth Bank’s financial planning division and ASIC.

Whistleblower Jeff Morris, who reported the misconduct of the bank to ASIC six years ago, said in an article for The Sydney Morning Herald that neither the bank nor ASIC should be in control of the compensation program.

Tuesday, December 26, 2017

Yesterday, at least four were killed and eleven were injured near the Slavyansky Bulvar Metro station in Moscow, Russia, after a bus ran down the steps at the entrance, officials stated. According to an emergency services source reported through state news media, fifteen were injured, and five died in the incident.

The incident happened in an icy situation. The bus drove onto the pavement and down the steps leading to the station. The police reportedly arrested the driver. News agencies reported the driver was not under the influence of alcohol. The driver told investigators the bus suddenly moved, and although he tried to stop it, the brakes did not work. A reported emergency services source said the accident might be due to brake failure.

According to Interfax news agency, the bus was less than a year old. Moscow’s mayor Sergei Sobyanin said he had ordered all Moscow buses to be inspected.

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Thursday, October 12, 2006

The Blunkett diaries, being serialised in the Guardian, claim that Gordon Brown opposed the war against Iraq. Only at the last minute did he give in, according to the diaries, when he realised that Blair would sack him otherwise.

Gordon Brown, interviewed by the Guardian, said he did not think Blunkett had ever said such a thing and that, if he was reported as having done so, he was being misquoted.

The diary entries are contemporary with the events and were recorded shortly after the Cabinet meeting on Iraq.

Monday, October 29, 2007

On Monday, October 22, as the latest Wikimedia fundraiser began, Wikinews reporter Brian McNeil thought his own small donation could be turned into a bigger donation by his buying some advertising on a popular website and encouraging others to contribute. With this in mind he approached Howard Tayler, creator of the Schlock Mercenary webcomic.

Tayler’s response was not as McNeil expected, prompting a Wikinews investigation. Tayler refused to help the foundation raise money although he conceded that he does sometimes use the site. Instead he explained that some members of the webcomic community feel slighted by Wikipedia because over 50 articles on webcomics were deemed not to meet their notability guidelines and were deleted during January and February of 2007. Some members of the webcomics community considered this unacceptable. Whilst some of the comic related articles deleted did not qualify for inclusion in the encyclopedia under Wikipedia guidelines, the deletion of a large number of articles in such a short time period struck some webcomics writers and fans as a selective purge.

Much of the criticism has been focused on Wikipedia editor Dragonfiend, who has described notability as “whether a topic has been noted by independent reputable sources”. She has said that “If we include every article that anyone wants to write, then the encyclopedia becomes useless because nobody can find the actual needle of worthwhile information on a topic hidden in that hay stack of trivia.” She has said Wikipedia should only have articles on webcomics like Penny Arcade, Get Your War On, Fetus-X, and Achewood.

This deletion of numerous webcomic articles has not sat well with some in the webcomic community. Modern Tales editor and Websnark blogger Eric Burns has written that “There are people — and Dragonfiend is clearly one of them — who are clearly going through Wikipedia looking for articles that should be weeded out as non-notable. and they’re doing it in fields they clearly — I mean, clearly — have no interest, experience or knowledge.”

Erfworld and PartiallyClips writer Rob Balder has expressed similar viewpoints, calling the deletion of the webcomics articles a “goddamned crime” and describing a “deletionist jihad” by “the politest bunch of book-burning assholes on the planet”. Balder also labelled “Deletionism” as a form of “naughtymancy” magic in Erfworld. Deletionism refers to the Wikipedia ideology that favours relatively rigorous standards for maintaining access to articles, as opposed to inclusionism which favours keeping and amending problematic articles.

There is concern among some webcomic groups that the notability guidelines are too rigorous for the typical webcomic. The standards usually require significant coverage in reliable sources that are independent of the subject, which is rare since even comics with dedicated followings do not always attract mainstream book publishers or reviews from mainstream journalists. It seems that this policy has alienated webcomic artists and fans and discouraged them from contributing to Wikipedia.

Conflicts such as this are not uncommon. Members of a Wikimedia Foundation mailing list pointed to other examples where the application of the rules has been perceived to be selective, leaving other communities disgruntled with a variety of Wikimedia projects, not just Wikipedia.

Monday, March 21, 2005

Portal and search company Yahoo! has purchased Ludicorp Research and Development Ltd., the private corporation which owns the photo sharing site Flickr. The news was officially disclosed in a Sunday posting to the corporation’s staff blog and is credited to Caterina Fake, Flickr’s vice president of marketing and community. The posting announced the sale, but did not disclose details of the deal. In a report by Silicon.Com, Yahoo! spokeswoman Joanna Stevens confirmed the deal on Sunday but also did not disclose the terms.

Both Fake and Stevens said Flickr will remain independent. Stevens added that Flickr’s employees will relocate to the Yahoo! headquarters in Sunnyvale, California later this year.

Rumors of the sale have been circulating amongst bloggers for some time, though neither company would confirm or deny the rumored sale. Other rumors had Google or AOL as Flickr’s probable suitor.

Flickr allows users to upload pictures from their computers, digital cameras, or camera phones to a personal website where they can display them, engage in photo blogging and create photo albums. The graphics may be licensed under a variety copyright license schemes including public domain, and photo owners can be easily contacted through the website.

Yahoo! had earlier announced Yahoo! 360°, a blogging service with sharing privileges and integration with other Yahoo! services such as internet broadcasting and instant messaging.

Tuesday, January 3, 2006

Three miners have escaped uninjured after being trapped underground by a mineshaft fire on Tasmania’s west coast. The men took shelter in a chamber more than a kilometre underground. A worker noticed smoke coming from a shaft at Avebury nickel mine on Trial Harbour Road near Zeehan at 7.45am.

The blaze started after a truck working 400 metres underground toppled and caught fire. It took nearly five hours for rescue teams to bring the blaze under control, move the burning truck and reach the trapped miners.

Allegiance Mining chairman Tony Howland-Rose said the workers were safe. “The emergency response procedures in place at Avebury were activated and resulted in the vehicle fire being extinguished and the safe rescue of the miners,” Mr Howland-Rose said.

Ambulance crews say the men appear to be in good health. Queenstown Police Inspector Mark Beech-Jones says rescue workers reached the men just before midday.

“We’ve dispatched a number of ambulance service personnel there just to give them a check up but from our initial discussions with them, they are fine,” he said.

The Avebury nickel mine is a new project for the Sydney-based company – Allegiance Mining. Allegiance suspended trading on the stock exchange this morning. Mr Howland-Rose said the suspension of trading would be in place until it became clear what had happened at the mine.

The mine is undergoing a $60 million redevelopment and was due to resume mining later this year.

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